Thats a hard question...but il just break them down to categories since i can give a concrete answer.
Dr. Tenma wins the perseverance award for keeping the "I believe in the goodness in Man" attitude throughout the whole series.
For awesomeness (you'll know why later, i dont want to give spoilers), Id say Wolfgang Grimmer.
Johann Liebert has the Calmest face Ive seen in all the animes I have seen to date. He reminds me of Dr. Lecter.
So far, whose your favorite character?